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DcR2 (Decoy Receptor 2, CD264, TNF-related Apoptosis-inducing Ligand Receptor 4, TRAIL Receptor 4, TRAILR4, TRAIL-R4, TRAIL Receptor with a Truncated Death Domain, TRUNDD, Tumor Necrosis Factor Receptor Superfamily Member 10D, TNFRSF10D, UNQ251/PRO288)

Cat no: D1500-01B

DcR2 (Decoy Receptor 2, CD264, TNF-related Apoptosis-inducing Ligand Receptor 4, TRAIL Receptor 4, TRAILR4, TRAIL-R4, TRAIL Receptor with a Truncated Death Domain, TRUNDD, Tumor Necrosis Factor Receptor Superfamily Member 10D, TNFRSF10D, UNQ251/PRO288)

TRAIL (also known as Apo-2L) is a member of the tumor necrosis factor (TNF) ligand family that rapidly induces apoptosis in a variety of transformed cell lines. A fourth member of the emerging TRAIL receptor family, TRAIL-R4, has signaling capacity similar to that of TRAIL-R1 and TRAIL-R2 with respect to NF-kappaB activation, but differs in its inability to induce apoptosis. Like TRAIL-R1 and TRAIL-R2, this receptor shows widespread tissue expression. The human TRAIL-R4 gene has been mapped to chromosome 8p22-21, clustered with three other TRAIL receptors.\n\nApplications:\nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 1:500-1:1000\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

D1500-01B

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, 0.02% sodium azide.

P Type

Pab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG

References

1. Degli-Esposti M.A. et al. Immunity 1997 Dec;7(6):813-20

Additional Info

Recognizes human TRAIL Receptor 4.

Alternative Names

Tumor Necrosis Factor Receptor Superfamily, Member 10d, Decoy with Truncated Death Domain

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