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Products Dectin-1 (C-type Lectin Domain Family 7 Member A, Dendritic Cell-associated C-type Lectin 1, DC-associated C-type Lectin 1, Beta-glucan Receptor, beta-GR, C-type Lectin Superfamily Member 12, CLEC7A, BGR, CLECSF12, DECTIN1, UNQ539/PRO1082) (Biotin)
| Catalogue number: | D1876-48P4 |
| Reactivities: | Mouse |
| Hosts: | Rat |
| Applications: | Flow Cytometry |
| Conjugates: | Biotin |
| Size: | 100ug |
| Form: | Supplied as a liquid in PBS, pH 7.4, 1% BSA, 0.09% sodium azide. Labeled with Biotin. |
| P type: | Mab |
| Isotype: | IgG2b |
| Purity: | Purified by Protein G affinity chromatography. |
| References: | 1. Brown, G. D. et al. (2002) Dectin-1 is a major beta-glucan receptor on macrophages. J. Exp. Med. 196:407-412.2. Taylor, P. R. et al. (2002) The beta-glucan receptor, Dectin-1 is predominantly expressed on the surface of cells of the monocyte/macrophage and neutrophil lineages. J. Immunol. 169:3876-3882.3. Reid, D.M. et al. (2004) Expression of the beta-glucan receptor, Dectin-1, on murine leukocytes in situ correlates with its function in pathogen recognition and reveals potential roles in leukocyte interactions. J. Leuk. Biol. 76:86-94.4. Underhill, D.M. et al. (2005) Dectin-1 activates Syk tyrosine kinase in a dynamic subset of macrophages for reactive oxygen production. Blood 106:2543-2550. |
| Additional info: | Recognizes mouse beta-glucan receptor, also known as Dectin-1. Dectin-1 is predominantly expressed by cells of the monocyte/macrophage and neutrophil lineages, but also at lower levels by dendritic cells and a subpopulation of T cells. |
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