Home  >  Products  >  Dexras1 (Ras dexamethasone induced 1)
Dexras1 (Ras dexamethasone induced 1)

Dexras1 (Ras dexamethasone induced 1)

Cat no: D3221-96T

Supplier: United States Biological
Star_fadedStar_fadedStar_fadedStar_fadedStar_faded
0 reviews | Write a Review Pencil
Read More on Supplier Website
Dexras1 (Ras dexamethasone induced 1) belongs to the Ras superfamily of GTPases and was initially identified as a dexamethasone inducible gene (1,2). Dexras1 reportedly regulates several distinct signal transduction pathways, including MAPK signaling, NMDA receptor-nitric oxide-mediated signaling, and pathways involving adenylyl cyclases (3-5). Dexras1 can directly modulate FE65-APP-mediated transcription and regulate the photic sensitivity of the mammalian circadian clock (6,7). Applications: Suitable for use in Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:1000. Incubate membrane with diluted antibody in 5% w/v BSA, 1X TBS, 0.1% Tween-20 at 4 degrees C with gentle shaking, overnight. Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: D3221-96T
Reactivities: Human
Hosts: Rabbit
Applications: Western Blot
Size: 100ul
Form: Supplied in 10mM sodium HEPES pH 7.5, 150mM NaCl, 100ug/ml BSA and 50% glycerol.
P type: Pab
Isotype: IgG
Purity: Purified by Protein A affinity chromatography.
References: 1. Kemppainen, R.J. and Behrend, E.N. (1998) J Biol Chem 273, 3129-31, 2. Tu, Y. and Wu, C. (1999) Biochim Biophys Acta 1489, 452-6, 3. Fang, M. et al. (2000) Neuron 28, 183-93, 4. Graham, T.E. et al. (2004) Biochem Biophys Res Commun 316, 307-12, 5. Nguyen, C.H. and Watts, V.J. (2005) Biochem Biophys Res Commun 332, 913-20, 6. Cheng, H.Y. et al. (2006) J Neurosci 26, 12984-95, 7. Lau, K.F. et al. (2008) J Biol Chem 283, 34728-37.
Additional info: Recognizes human Dexras1. Cross-reacts with a 60 kDa protein of unknown origin.

Get Quote

  • Best Price Guaranteed
  • Quick Response Time
  • Exclusive Promotions
Enquiry_down_arrow
United States Biological
Get a Quote Direct from
United States Biological

By submitting this form you agree to your details being passed to United States Biological for the purpose of generating the best quote*
See Full Product Listings >
Button_on Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave Button_off_biosave