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Factor XI

Cat no: F0018-55

Factor XI

Factor XI is a plasma glycoprotein which circulates in a non-covalent complex with high molecular weight kininogen. The mature molecule is synthesized in the liver and is a two-chain homodimer with a molecular weight of approximately 160,000. It is estimated that 5% of the total mass is attributable to carbohydrate (2). The two identical monomers have molecular weights of 80,000, and are joined together by disulfide bonds. Thus by SDS-PAGE analysis, factor XI appears as a single band both non-reduced (Mr=160,000), and reduced (Mr=80,000).

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SPECIFICATIONS

Catalog Number

F0018-55

Size

100ug

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in 50% glycerol, H2O.

P Type

Mab

Purity

Purified

Isotype

IgG

Additional Info

Recognizes human Factor XI, iodine-125 labeled Factor XI, human \nFactor XIa, BEGRck-factor XIa. Does not recognize mouse Factor XI (Western Blot in plasma)

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