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FasL, Soluble, Recombinant, Human (APO-1L, CD95L, CD178, TNFSF6, Fas Ligand)

FasL, Soluble, Recombinant, Human (APO-1L, CD95L, CD178, TNFSF6, Fas Ligand)

Cat no: 044784

Supplier: United States Biological
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FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. Is involved in cytotoxic T cell mediated apoptosis and in T cell development. Biological Activity: Induces apoptosis of human Jurkat T cells at a concentration of <1ng/ml in the presence of 0.1 to 1ug/ml TNF Ligands Enhancer. In the absence of TNF Ligands Enhancer, FasL is working at 50-100 fold higher concentrations. Sequence: The extracellular domain of human FasL (aa 103-281) is fused at the N-terminus to a FLAG(R)-tag. Storage and Stability: Short-term Storage: +4 degrees C Long-term Storage: -20 degrees C Stable for at least 6 months after receipt when stored at -20 degrees C.
Catalogue number: 044784
Size: 10ug
Form: Supplied as a lyophilized powder from a 0.2um filtered solution in PBS pH 7.2.
Purity: >95% (SDS-PAGE)
Alternative names: APO-1L, CD95L, CD178, TNFSF6, Fas Ligand

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