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Fcn1 (Ficolin-1, Collagen/Fibrinogen Domain-containing Protein 1, Ficolin-A, Ficolin-alpha, M-ficolin, Fcna)

Cat no: 029771

Fcn1 (Ficolin-1, Collagen/Fibrinogen Domain-containing Protein 1, Ficolin-A, Ficolin-alpha, M-ficolin, Fcna)

Ficolin-1 also known as M-Ficolin is a pattern recognition molecule of the lectin complement activation pathway. It is expressed mostly in monocytes, nuetrophils and in type II alveolar epithelial cells. Ficolin-1 is detected on the surface of circulating monocytes but is not present in the plasma. Ficolin-1 has a 28 aa signal sequence, an N-terminal collagen domain and a Cterminal fibrinogen-like (FBG) domain that contain a calcium binding site and a potential Nglycosylation site.\n\nApplications:\nSuitable for use in Western Blot. Other applications not tested.\n\nRecommended Dilution:\nWestern Blot: 0.5-4ug/ml\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

029771

Size

100ug

Applications

WB

Hosts

Rabbit

Reactivities

Hum, Mouse, Rat

Form

Supplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol.

P Type

Pab

Purity

Purified by affinity chromatography.

Isotype

IgG

Additional Info

Recognizes rat Ficolin-1 at ~33kD and a 37kD Ficolin-1 precursor. Species Crossreactivity: human and mouse.

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