Home  >  Products  >  Filamin A (FLN, FLNA, FLN1, Filamin 1, Endothelial Actin-binding Protein, Actin-binding Protein 280, ABP280, ABP-280, Non-muscle Filamin)
Filamin A (FLN, FLNA, FLN1, Filamin 1, Endothelial Actin-binding Protein, Actin-binding Protein 280, ABP280, ABP-280, Non-muscle Filamin)

Filamin A (FLN, FLNA, FLN1, Filamin 1, Endothelial Actin-binding Protein, Actin-binding Protein 280, ABP280, ABP-280, Non-muscle Filamin)

Cat no: F4510-79B

Supplier: United States Biological
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Actin-binding protein, or filamin, is a 280kD protein that crosslinks actin filaments into orthogonal networks in cortical cytoplasm and participates in the anchoring of membrane proteins for the actin cytoskeleton. Remodeling of the cytoskeleton is central to the modulation of cell shape and migration. Filamin A, encoded by the FLNA gene, is a widely expressed protein that regulates reorganization of the actin cytoskeleton by interacting with integrins, transmembrane receptor complexes, and second messengers.[supplied by OMIM] Applications: Suitable for use in Western Blot and Immunoprecipitation. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: F4510-79B
Reactivities: Human, Mouse
Hosts: Rabbit
Applications: Immunoprecipitation, Western Blot
Size: 100ul
Form: Tris-buffered Saline 0.1% BSA
P type: Pab
Purity: Purified by immunoaffinity chromatography.
Alternative names: FMD, MNS, NHBP, OPD1, OPD2
Additional info: Species Crossreactivity: Human and Mouse.

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