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Heat Shock Protein 90 D7a (HSP90 alpha, HSP86)

Cat no: H1832-82E

Heat Shock Protein 90 D7a (HSP90 alpha, HSP86)

Hsp90 is a highly conserved and essential stress protein that is expressed in all eukaryotic cells. From a functional perspective, hsp90 participates in the folding, assembly, maturation, and stabilization of specific proteins as an integral component of a chaperone complex (4-7). Despite its label of being a heat-shock protein, hsp90 is one of the most highly expressed proteins in unstressed cells (1

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SPECIFICATIONS

Catalog Number

H1832-82E

Size

25ug

Applications

IHC, IP, WB

Hosts

Mouse

Reactivities

Hum, Mouse, Rat, Bov, Ch/Bird, Prc, Rabbit

Form

Supplied as a liquid in PBS buffer, 0.09% sodium azide and 50% glycerol.

P Type

Mab

Purity

Purified by ammonium sulfate precipitation.

Isotype

IgG1

References

1. Schuh S. et al. (1985) J Biol Chem. 260 (26): 14292-14296. 2. Lipsich L.A., Cutt J.R. and Brugge J.S. (1982) Mol. Cell Biol. 2(7): 875-880. 3. Brugge J.S., Yonemoto W., and Darrow D. (1983) Mol. Cell. \nBiol. 3(1): 9-19. 4. Arlander SJH, et al. (2003) J Biol Chem 278: 52572-52577. 5. Pearl H, et al. (2001) Adv Protein Chem 59: 157-186. 6. Neckers L, et al. (2002) Trends Mol Med 8:S55-S61. 7. Pratt W, Toft D. (2003) Exp Biol Med 228:111-133. 8. Pratt W, Toft D. (1997) Endocr Rev 18: 306

Additional Info

Recognizes human samples of hsp90 alpha. Species Crossreactivity: bovine, chicken, human, mouse, porcine, rat, rabbit.

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