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Heme Assay Kit, BioAssay(TM)

Cat no: H1847-64

Heme Assay Kit, BioAssay(TM)

Heme is one important member of the porphyrin family. It is synthesized in both mitochondria and cytoplasm, and is a key prosthetic group for various essential proteins such as hemoglobin, cytochromes, catalases and peroxidases. Heme determination is widely practiced by researchers of various blood diseases.\n\nSimple, direct and automation-ready procedures for measuring heme concentration are becoming popular in Research and Drug Discovery. Heme Assay Kit is based on an improved aqueous alkaline solution method, in which the heme is converted into a uniform colored form. The intensity of color, measured at 400 nm, is directly proportional to the heme concentration in the sample. The optimized formulation substantially reduces interference by substances in the raw samples and exhibits high sensitivity.\n\nApplications:\nDirect Assays: total heme in blood, serum, plasma, urine, heme-carrying enzymes. Pharmacology: effects of drugs on heme metabolism.\nDrug Discovery: HTS for drugs that modulate heme levels.\n\nKey Features:\nSensitive and accurate. Linear detection range 0.6

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SPECIFICATIONS

Catalog Number

H1847-64

Size

1Kit

References

1. Mingone, C.J. et al (2006). Protoporphyrin IX generation from delta-aminolevulinic acid elicits pulmonary artery relaxation and soluble guanylate cyclase activation. Am J Physiol Lung Cell Mol Physiol 291: L337

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