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Hepatitis B Surface Antigen, ayw3 (HBsAg)

Cat no: H1915-93A

Hepatitis B Surface Antigen, ayw3 (HBsAg)

Hepatitis B virus causes type B hepatitis and it belongs to hepadnavirus family. It is spherical in shape with a diameter of 42nm. It contains a 27nm partially double stranded DNA core enclosed within a lipoprotein coat. The antigenic activity of the nucleocapsid core is designated as hepatitis B core antigen. The antigens in the outer surface are called as hepatitis B virus surface antigens. Core antigens are localized within the nuclei whereas the surface antigens are present in the cytoplasm of the infected cells. Antibodies to surface antigens appear in circulation at an early stage of infection whereas the antibodies to the core antigens are detected after several weeks.\n\nApplications:\nSuitable for use in Immunohistochemistry. Other applications have not been tested. \n\nRecommended Dilutions: \nImmunohistochemistry (Formalin/paraffin): 1:12.5-1:25 for 30 minutes at RT. No special pretreatment is required for immunohistochemical staining of formalin/paraffin tissues. \n\nPositive Control: Hepatitis B virus infected liver\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

H1915-93A

Size

500ul

Applications

ELISA, IHC

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, 0.09% sodium azide, 40% glycerol.

P Type

Mab

Purity

Supernatant

Isotype

IgG1

References

1. Swenson P D, et al. (1988) In: Viral hepatitis and Liver Disease. Alan R. Liess, Inc. p627.

Additional Info

Recognizes a protein in the outer surface coat of human hepatitis B virus.

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