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KDM5C (MRXJ, SMCX, MRXSJ, XE169, MRXSCJ, JARID1C, DXS1272E)

Cat no: 143205

KDM5C (MRXJ, SMCX, MRXSJ, XE169, MRXSCJ, JARID1C, DXS1272E)

This gene is a member of the SMCY homolog family and encodes a protein with one ARID domain, one JmjC domain, one JmjN domain and two PHD-type zinc fingers. The DNA-binding motifs suggest this protein is involved in the regulation of transcription and chromatin remodeling. Mutations in this gene have been associated with X-linked mental retardation. Alternative splicing results in multiple transcript variants. \n\nApplications: \nSuitable for use in Western Blot and Immunocytochemistry. Other applications not tested. \n\nRecommended Dilution:\nWestern Blot: 1:1000\nImmunocytochemistry: 1:150\nOptimal dilutions to be determined by the researcher. \n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

143205

Size

100ul

Applications

ICC, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in 0.1M Tris-Glycine, pH 7.4, 150mM NaCl, 0.2% sodium azide, 50% glycerol.

P Type

Mab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG2a

Additional Info

Recognizes endogenous levels of KDM5C. Does not corss-react with related proteins. Species Crossreactivity: human

Alternative Names

(MRXJ, SMCX, MRXSJ, XE169, MRXSCJ, JARID1C, DXS1272E)

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