Home  >  Products  >  MPI, Recombinant, Human, aa1-362, His-tag (Mannose-6-phosphate Isomerase, Phosphohexomutase, Phosphomannose Isomerase, PMI, PMI1)

MPI, Recombinant, Human, aa1-362, His-tag (Mannose-6-phosphate Isomerase, Phosphohexomutase, Phosphomannose Isomerase, PMI, PMI1)

Cat no: 029671


Supplier: United States Biological
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MPI, belongs to the mannose-6-phosphate isomerase type 1 family, and is expressed in all tissues, more abundantly in heart, brain and skeletal muscle. Localized to the cytoplasm, MPI utilizes zinc as a cofactor and catalyzes the interconversion of fructose-6-phosphate and mannose-6-phosphate. Mutations in the MPI gene were found in patients with carbohydrate-deficient glycoprotein syndrome, type Ib. Source: Recombinant corresponding to aa1-362 from human MPI, fused to His-tag, expressed in E.coli. AA Sequence: MGSSHHHHHH SSGLVPRGSH MAAPRVFPLS CAVQQYAWGK MGSNSEVARL LASSDPLAQI AEDKPYAELW MGTHPRGDAK ILDNRISQKT LSQWIAENQD SLGSKVKDTF NGNLPFLFKV LSVETPLSIQ AHPNKELAEK LHLQAPQHYP DANHKPEMAI ALTPFQGLCG FRPVEEIVTF LKTAAGNNME DIFGELLLQL HQQYPGDIGC FAIYFLNLLT LKPGEAMFLE ANVPHAYLKG DCVECMACSD NTVRAGLTPK FIDVPTLCEM LSYTPSSSKD RLFLPTRSQE DPYLSIYDPP VPDFTIMKTE VPGSVTEYKV LALDSASILL MVQGTVIAST PTTQTPIPLQ RGGVLFIGAN ESVSLKLTEP KDLLIFRACC LL Molecular Weight: ~41.9kD Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Catalogue number: 029671
Size: 100ug
Form: Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.4M urea, 5% glycerol.
Purity: ~90% (SDS-PAGE)
References: 1. Schollen E., et al. (2000) Hum Mutat. 16:247-252. 2. Proudfoot A E., et al. (1996) Biochem J. 318:437-442.

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