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NUP62, Recombinant, Human (Nuclear Pore Glycoprotein p62, 62kD Nucleoporin, Nucleoporin Nup62)

Cat no: 149549


Supplier: United States Biological
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Protein p62 preferentially binds multiubiquitin chains and forms a novel cytoplasmic structure "sequestosome" which serves as a storage place for ubiquitinated proteins. Source: Recombinant protein corresponding to human p62, expressed in E. coli. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Aliquot to avoid repeated freezing and thawing and store at -70 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Catalogue number: 149549
Applications: ELISA, Western Blot
Size: 25ug
Form: Supplied as a liquid in 20mM Tris-HCl, 150mM sodium chloride, 1mM EDTA, 5mM glutathione, 0.5mM GSSH, 10% glycerol.
Purity: ~90% (Nickel NTA Affinity Chromatography)
References: 1. Eng M Tan (1999). A Novel Cytoplasmic Protein with RNA-binding Motifs is an Autoantigen in Human Hepatocellular Carcinoma. J Exp Med 189(7):1101-1110. 2. Moscat J (2005). The p62 scaffold regulates nerve growth factor -induced NF-kapppa B activation by influencing TRAF6 polyubiquitination. J Biol Chem; 280(42):35625-9.

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