PTP4A1 (Protein Tyrosine Phosphatase Type IVA 1, PTP(CAAXI), Protein-tyrosine Phosphatase 4a1, Protein-tyrosine Phosphatase of Regenerating Liver 1, PRL-1, PRL1, PTPCAAX1)

Protein tyrosine phosphatase which stimulates progression from G1 into S phase during mitosis. May play a role in the development and maintenance of differentiating epithelial tissues. Enhances cell proliferation, cell motility and invasive activity, and promotes cancer metastasis.\n\nApplications:\nSuitable for use in ELISA and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1:2000\nWestern Blot: 1-3ug/ml, lysates of cell lines A549 and HeLa observed on ~21kD bands\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

P9109-45X

Size

100ug

Applications

ELISA, WB

Hosts

Goat

Reactivities

Hum, Mouse, Rat, Can

Form

Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.

P Type

Pab

Purity

Purified by immunoaffinity chromatography.

References

1. Peng Y, Genin A, Spinner NB, Diamond RH, Taub R. The gene encoding human nuclear protein tyrosine phosphatase, PRL-1. Cloning, chromosomal localization, and identification of an intron enhancer.\nJ Biol Chem 1998 Jul 3;273(27):17286-95.

Additional Info

Recognizes human PTP4A1. Species sequence homology: Canine, mouse and rat.