SH3BGR, ID (SH3BGR, SH3 domain-binding glutamic acid-rich protein, 21-glutamic acid-rich protein)

Proline-rich peptide sequences have been shown to play important roles in protein-protein interactions that occur in signal transduction pathways. SH3 domain binding glutamic acid-rich protein (SH3BGR), also designated 21-glutamic acid-rich protein (21-GARP), is a 239-amino acid protein differentially expressed in heart and skeletal muscle. Its proline-rich region contains the consensus sequence for an SH3-binding domain and its acidic C-terminal region contains a glutamic acid-rich domain which may assume a coiled-coil structure. SH3BGR may be part of a multimeric complex, as it contains 2 functional domains involved in protein-protein interactions.\n\nApplications:\nSuitable for use in Western Blot, ELISA\n\nRecommended Dilution:\nELISA: 1:1,000\nWestern Blot: 1:100-500\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Prices direct from United States Biological

Quick response times

Exclusive Biosave savings/discounts

SPECIFICATIONS

Catalog Number

041686

Size

200ul

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

P Type

Pab

Purity

Purified by Protein A affinity chromatography.

Isotype

IgG

References

Naukkarinen, J., et al. PLoS Genet. 6 (6), E1000976 (2010) :\nHu, Y.H., et al. BMC Genomics 7, 155 (2006) :\nSandri, C., et al. Hum. Genet. 114(5):517-519(2004)\nJiang, L.Q., et al. Hypertens. Res. 25(4):647-652(2002)\nScartezzini, P., et al. Hum. Genet. 99(3):387-392(1997)

Additional Info

Human

Alternative Names

SH3BGR, SH3 domain-binding glutamic acid-rich protein, 21-glutamic acid-rich protein