SLIT2 (Slit Homolog 2 Protein, Slit-2, SLIL3)

Cat no: S1014-19P

Supplier: United States Biological

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Slit-2 is thought to act as molecular guidance cue in cellular migration, and its function appears to be mediated by interaction with roundabout homolog (ROBO) receptors. It is a secreted protein known for its role of repulsion in axon guidance and neuronal migration that can also inhibit leukocyte chemotaxis induced by chemotactic factors. Applications: Suitable for use in ELISA and Immunohistochemistry. Other applications not tested. Recommended Dilution: ELISA: 1:1000 Immunohistochemistry (Paraffin): 4-8ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	S1014-19P
Reactivities:	Human, Mouse, Rat, Canine
Hosts:	Goat
Applications:	ELISA, Immunohistochemistry
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
References:	1. Lin L, Rao Y, Isacson O. Netrin-1 and slit-2 regulate and direct neurite growth of ventral midbrain dopaminergic neurons. Mol Cell Neurosci. 2005 Mar;28(3):547-55.
Additional info:	Recognizes human SLIT2. Species sequence homology: Canine, mouse and rat.

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SLIT2 (Slit Homolog 2 Protein, Slit-2, SLIL3)

Cat no: S1014-19P

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