SRD5A2 (3-oxo-5-alpha-steroid 4-dehydrogenase 2, 5 alpha-SR2, SR Type 2, Steroid 5-alpha-reductase 2, S5AR 2, Type II 5-alpha Reductase)

Cat no: S6505-08Q

Supplier: United States Biological

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Converts testosterone (T) into 5-alpha-dihydrotestosterone (DHT) and progesterone or corticosterone into their corresponding 5-alpha-3-oxosteroids. It plays a central role in sexual differentiation and androgen physiology. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:8000 Western Blot: 0.3ug/ml Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	S6505-08Q
Reactivities:	Human
Hosts:	Goat
Applications:	ELISA, Western Blot
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
References:	1. Vu TT, Hirst JJ, Stark M, Wright IM, Palliser HK, Hodyl N, Clifton VL. Changes in human placental 5alpha-reductase isoenzyme expression with advancing gestation: effects of fetal sex and glucocorticoid exposure. Reprod Fertil Dev. 2009;21(4):599-607.
Additional info:	Recognizes human SRD5A2.

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SRD5A2 (3-oxo-5-alpha-steroid 4-dehydrogenase 2, 5 alpha-SR2, SR Type 2, Steroid 5-alpha-reductase 2, S5AR 2, Type II 5-alpha Reductase)

Cat no: S6505-08Q

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