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STAT 1 (Signal Transducer and Activator of Transcription 1, Signal Transducer and Activator of Transcription 1 91kDa, Signal Transducer and Activator of Transcription 1 alpha/beta, STAT1, STAT-1, DKFZp686B04100, ISGF-3, STAT 91, STAT91, Transcription Fact

Cat no: S7969-05B1

STAT 1 (Signal Transducer and Activator of Transcription 1, Signal Transducer and Activator of Transcription 1 91kDa, Signal Transducer and Activator of Transcription 1 alpha/beta, STAT1, STAT-1, DKFZp686B04100, ISGF-3, STAT 91, STAT91, Transcription Fact

The protein encoded by this gene is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein can be activated by various ligands including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. This protein mediates the expression of a variety of genes, which is thought to be important for cell viability in response to different cell stimuli and pathogens. Two alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq]\n\nApplications: \nSuitable for use in ELISA, Immunofluorescence, and Western Blot. Other applications not tested.\n\nRecommended Dilution:\nELISA: 1ug/ml-3ng/ml\nWestern Blot: 1:500-1:1,000\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

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SPECIFICATIONS

Catalog Number

S7969-05B1

Size

100ul

Applications

ELISA, IF, WB

Hosts

Mouse

Reactivities

Hum

Form

Supplied as a liquid in PBS, pH 7.2. No preservative added (Azide free).

P Type

Mab

Purity

Purified by immunoaffinity chromatography.

Isotype

IgG2a

Additional Info

Recognizes human STAT1.

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