SV2A (Synaptic Vesicle Glycoprotein 2a, KIAA0736, OTTHUMP00000014065, PSEC0174)

Cat no: S8747-01C

Supplier: United States Biological

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Plays a role in the control of regulated secretion in neural and endocrine cells, enhancing selectively low-frequency neurotransmission. Positively regulates vesicle fusion by maintaining the readily releasable pool of secretory vesicles. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:64,000 Western Blot: 0.3-1ug/ml, observed in rat brain lysates on ~80kD bands Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4 degrees C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20 degrees C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Catalogue number:	S8747-01C
Reactivities:	Human, Mouse, Rat, Bovine, Canine, Porcine
Hosts:	Goat
Applications:	ELISA, Western Blot
Size:	100ug
Form:	Supplied as a liquid in Tris saline, 0.02% sodium azide, pH 7.3, 0.5% BSA.
P type:	Pab
Purity:	Purified by immunoaffinity chromatography.
References:	1. Dong M, Yeh F, Tepp WH, Dean C, Johnson EA, Janz R, Chapman ER. SV2 is the protein receptor for botulinum neurotoxin A. Science. 2006 Apr 28;312(5773):592-6. Epub 2006 Mar 16.
Additional info:	Recognizes rat SV2A. Species sequence homology: Bovine, canine, human, mouse and porcine.

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SV2A (Synaptic Vesicle Glycoprotein 2a, KIAA0736, OTTHUMP00000014065, PSEC0174)

Cat no: S8747-01C

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