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Troponin I, Cardiac, Canine (Troponin I, Cardiac Muscle, Cardiac Troponin I, TNNI3)

Cat no: T8665-13R

Troponin I, Cardiac, Canine (Troponin I, Cardiac Muscle, Cardiac Troponin I, TNNI3)

Troponin, working in conjunction with tropomyosin, functions as a molecular switch, regulating muscle contraction in response to changes in the intracellular Ca2+ concentration. Troponin consists of three subunits, the Ca2+-binding subunit troponin C (TnC), the tropomyosin-binding subunit troponin T (TnT), and the inhibitory subunit troponin I (TnI). Troponin I binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place, because of which myosin cannot bind to actin in relaxed muscle. When Calcium binds to the Troponin C it causes certain confomational changes which leads to dislocation of troponin I. The letter

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SPECIFICATIONS

Catalog Number

T8665-13R

Size

100ug

Applications

ELISA, WB

Form

Supplied as a liquid in 8M urea, 50mM tris-HCl, 100mM sodium chloride, 2mM EDTA, pH7.4, 5mM beta-mercaptoethanol. Preservative free.

Purity

~95% (SDS-PAGE). Purified by Ion Exchange chromatography and calcium dependent affinity chromatography.

Read more on Supplier website

Applications

ELISA

Reactivities

Hum

More info

Applications

IF

Hosts

Mouse

More info

Applications

ELISA, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, WB

Hosts

Mouse

Reactivities

Hum

More info

Applications

ELISA, FC, IHC, WB

Hosts

Mouse

More info

Applications

IHC, WB

Hosts

Rabbit

Reactivities

Hum

More info

Applications

ELISA, WB

Hosts

Rabbit

Reactivities

Hum

More info
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