Home  >  Products  >  Tubulin, alpha, phosphorylated (Tyr272) (Alpha Tubulin, Tubulin alpha Ubiquitous, H2-Alpha, K-alpha-1, TUBA3, Tubulin alpha 1 Chain, TUBA1, TUBA1A, Tubulin K alpha 1)

Tubulin, alpha, phosphorylated (Tyr272) (Alpha Tubulin, Tubulin alpha Ubiquitous, H2-Alpha, K-alpha-1, TUBA3, Tubulin alpha 1 Chain, TUBA1, TUBA1A, Tubulin K alpha 1)

Cat no: T9155-51


Supplier: United States Biological
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Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha-chain. An essential component of microtubules, alpha-tubulin is also a multigene family in many species (1). Familial amyloidosis, British type, is an autosomal dominant disease characterized by progressive dementia, spastic paralysis and ataxia. The identity of the accumulating amyloid is not known, thus preventing the definitive classification of the disease. Findings suggest that the C-terminal fragments of both alpha- and beta-tubulin are closely associated to the amyloid deposits of familial amyloidosis, British type (2). Applications: Suitable for use in Immunocytochemistry, Western Blot. Other applications not tested. Recommended Dilution: Western Blot: 1:25,000
Catalogue number: T9155-51
Reactivities: Human
Hosts: Rabbit
Applications: Immunocytochemistry, Western Blot
Size: 100ul
Form: Supplied as a liquid in 50 mM Tris-Glycine, pH 7.4, 0.15 M sodium chloride, 40% Glycerol, 0.01% sodium azide and 0.05% BSA.
P type: Mab
Isotype: IgG
Purity: Supernatant
Alternative names: Tubulin alpha-ubiquitous chain, Alpha-tubulin ubiquitous, Tubulin K-alpha-1
References: 1. Cowan NJ et al. Mol Cell Biol 3(10):1738-45, 1983 2. Baumann MH, et al. Biochem Biophys Res Commun 219(6):238-42.
Additional info: Recognizes human alpha-tubulin phosphorylated at tyrosine 272.

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