Varicella Zoster Virus, gp4, Strain Ellen (VZV)

VZV is a member of the human herpes virus family which causes two distinct clinical manifestations: childhood chickenpox (Varicella) and shingles (Zoster). Varicella is the outcome of the primary infection with VZV, whereas, Zoster is the result of VZV reactivation from latently infected sensory ganglia which occurs predominantly in aging and immuno-suppressed individuals.\n\nApplications: \nSuitable for use in Indirect Immunofluorescence and Immunoprecipitation. Other applications have not been tested.\n\nRecommended Dilution:\nOptimal dilutions to be determined by the researcher.\n\nStorage and Stability:\nMay be stored at 4 degrees C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20 degrees C. Aliquots are stable for at least 12 months at -20 degrees C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.

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SPECIFICATIONS

Catalog Number

V2100-12B

Size

500ug

Applications

IF, IP

Hosts

Mouse

Form

Supplied as a liquid in 20mM sodium phosphate dibasic, pH

P Type

Mab

Purity

Purified by Protein G affinity chromatography.

Isotype

IgG1

References

1. Sato, H., et al., (2003), \"Varicella-Zoster Virus ORF47 Protein Kinase, which is required for Replication in Human T cells, and ORF66 Protein Kinase which is expressed during Latency, are dispensable for establishment of Latency\", Journal of Virology, 77(20): 11180-11185. 2. Weller, T.H., (1979), \"Varicella and Herpes Zoster. In:Diagnostic Procedures for Viral, Rickettsial and Chlamydial Infections\", (Lennette, E.H. and Schmidt, N.J., eds.) American Public Health Associations, Inc. Washington D.C., pp 375-398. 3. Drew, W.L., et al., (1980), \"Rapid diagnosis of varicella-zoster virus infection by direct immuno-fluorescence\", Am. J. Clin. Pathol., 73: 699-701. 4. Davison et al, (1986), \"New common nomenclature for glycoprotein gene of varicella-zoster virus and their glycosylated products\", J. Virol., 57: 1195-1197.

Additional Info

Recognizes VZV glycoprotein IV and to a lesser extent VZV glycoprotein I (VZVgE) by immunoprecipitation test. This clone reacts with both precursor and mature glycoprotein IV (VZVgI).