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(Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer)

(Z)-4-Hydroxy-N-desmethyl Tamoxifen (contains up to 10% E isomer)

Cat no: 013646

Supplier: United States Biological
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A novel active metabolite of the anti-cancer drug Tamoxifen. It showed potent ER binding property, blocked estrogen stimulated growth of breast cancer cell and half maximal inhibition of estrogen responsive gene expression in ER pos. human breast cancer cell line. Form: Off-White to Pink Solid Melting Point: 127-129 degrees C Solubility: Chloroform, Methanol
Catalogue number: 013646
Size: 1mg
Form: Off-White to Pink Solid
Alternative names: 4-[(1Z)-1-[4-[2-(Methylamino)ethoxy]phenyl]-2-phenyl-1-buten-1-yl]phenol;
References: Furr, B., et al.: Pharmacol. Ther., 25, 127

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