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Damaged DNA binding protein (DDB) is a heterodimer composed of two subunits, p127 and p48, which are designated DDB1 and DDB2, respectively. The DDB...
Dynactin, a multisubunit complex, is a cytoplasmic dynein-interacting protein that functions as the
Decorin is a small leucine-rich proteoglycan (SLRP) family member that consists of a glycosaminoglycan chain-containing core protein. The core protein...
The dCK/dGK family of proteins includes 4 different deoxyribonucleoside kinases including the cytoplasmic (TK1) and mitochondrial (TK2) thymidine kinases,...
P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous and xenobiotic compounds. P450...
CYP17A (17(alpha)-hydroxylase/17,20-lyase) is important for the conversion of pregnenolone and progesterone to dehydroepiandrosterone (DHEA) and...
?CYP11A1, also known as cytochrome P450C11A1, cytochrome P450scc and cytochrome P450, subfamily XIA, is an enzyme that catalyzes the first step of steroid...
Cytochrome P450 2E1 (CYP2E1) localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes...
Cytochrome P450 1B1 (CYP1B1) is a key enzyme involved in the production of potentially carcinogenic estrogen metabolites and the activation of environmental...
P450 enzymes constitute a family of monooxygenase enzymes that are involved in the metabolism of a wide array of endogenous levels of and xenobiotic...
Mox1 and the glycoprotein gp91-phox are largely related proteins that are essential components of the NADPH oxidase. The superoxide-generating NADPH oxidase...
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S,...
The (alpha), (beta), (delta), and (gamma) -catenins are proteins that bind to the highly conserved, intracellular cytoplasmic tail of E-cadherin....
Casein kinase I (also designated CKI) and casein kinase II (CKII) compose a family of serine/threonine protein kinases which are present in all eukaryotes...
The human IL-3, IL-5 and GM-CSF receptors are each composed of both unique a subunits and a common (beta) subunit. The a subunits are low affinity ligand...
The Claudin superfamily consists of many structurally related proteins in humans. These proteins are important structural and functional components of tight...
Clusterin, also designated complement lysis inhibitor (CLI), apolipoprotein J (APOJ), sulfated glycoprotein 2 (SGP2), SP-40 and testosterone-repressed...
Nicotinic acetylcholine receptors (AChRs) are found at the postsynaptic membrane of the neuromuscular junction and bind acetylcholine molecules, allowing...
The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, breakdown of...
The muscarinic acetylcholine receptors (mAChR) mediate a variety of cellular responses, including inhibition of adenylate cyclase, brea own of...
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