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AMPK is a heterotrimeric complex comprising a catalytic (alpha) subunit and regulatory (beta) and (gamma) subunits. It protects cells from stresses that...
AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2...
AKT, also known as protein kinase B (PKB), is a 57 kDa serine/threonine protein kinase. There are three mammalian isoforms of Akt: AKT1 (PKB alpha), AKT2...
Adducins are a family of cytoskeletal proteins encoded by three genes (alpha, beta, gamma). Adducin is a heterodimeric protein that consists of related...
The translation of proteins from eukaryotic mRNA is initiated by the multisubunit complex eIF-4F, which associates with the mRNA 5' cap structure. eIF-4E, a...
14-3-3 proteins regulate many cellular processes relevant to cancer biology, notably apoptosis, mitogenic signaling and cell-cycle checkpoints. Seven...
The Ras-related superfamily of guanine nucleotide binding proteins, which includes the R-Ras, Rap, Ral/Rec and Rho/Rab subfamilies, exhibit 30-60% homology...
Neuromedin U (NmU) is a vertebrate peptide which stimulates uterine smooth muscle contraction and causes selective vasoconstriction. Like most other active...
Function: May be signaling molecules that resemble neuropeptides. Ligand for alpha-neurexins. Subcellular location: Secreted. Tissue specificity: Highest...
Function: May be signaling molecules that resemble neuropeptides and that act by binding to alpha-neurexins and possibly other receptors. Subcellular...
NCAM2 is a cell adhesion molecule belonging to the immunoglobulin superfamily. It is differentially expressed in the developing and mature olfactory...
The p30-15 monoclonal antibody recognizes CD337 also known as activating NK receptor NKp30 (NKp30), and natural cytotoxicity triggering receptor 3. NKp30 is...
NKp46 (lymphocyte antigen 94, LY94) is a natural cytotoxicity receptor that belongs to the immunoglobulin superfamily and is expressed by all resting or...
ME1 (Malic enzyme 1), also known as NADP-ME, MES or HUMNDME, is a 572 amino acid cytoplasmic protein that belongs to the malic enzyme family. Expressed...
The NADP(H)-dependent enzyme leukotriene 12-hydroxy dehydrogenase (LTB4DH) catalyzes double bond reductions and oxo-reductions in lipoxins (15-oxo-lipoxin A...
A small number of complex I subunits are the products of mitochondrial genes (subunits 1-7), while the remainder are nuclear encoded and imported from the...
NDUFA4 (NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4), also known as MLRQ, is an 81 amino acid protein that localizes to the matrix side of the...
MDFI is a transcription factor that negatively regulates other myogenic family proteins. Studies of the mouse homolog, I-mf, show that it interferes with...
Mitochondrial ribosomes consist of a large 39S subunit and a small 28S subunit, both of which are comprised of multiple mitochondrial ribosomal proteins...
Mammalian mitochondrial ribosomes (mitoribosomes) are responsible for protein synthesis within the mitochondrion. The mitoribosomes are composed of a 4:1...
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