POLB, belongs to the DNA polymerase type-X family. In eukaryotic cells, DNA polymerase beta (POLB) performs base excision repair (BER) required for DNA...
DERA, belongs to the deoC/fbaB aldolase protein family involved in the carbohydrate degradation pathway. This protein catalyzes the conversion of...
CYB5A, belongs to the cytochrome b5 family. Cytochrome b5 is a membrane bound hemoprotein which function as an electron carrier for several membrane bound...
RYGD belongs to the beta/gamma-crystallin family. Crystallins are the dominant structural components of the vertebrate eye lens. Mammalian lens crystallins...
CRP belongs to the pentaxin family. This protein is found in the blood, its levels rise dramatically during inflammatory processes occurring in the body....
COPS8, is one of the eight subunits of COP9 signalosome, a highly conserved protein complex that functions as an important regulator in multiple signaling...
C8G, is one of three polypeptides (along with C8 alpha and C8 beta) that constitutes C8, a component of the complement system. C8 participates in the...
CNOT7, is a ubiquitous transcription factor. It is a component of the CCR4 complex which functions as a general transcription regulation complex. CNOT7 also...
CFL2 belongs to the actin-binding proteins ADF family that contains 1 ADF-H domain. Cofilin is a widely distributed intracellular actin-modulating protein...
CDKN1B, belongs to the Cip/Kip family of cyclin dependent kinase (Cdk) inhibitor proteins. This protein binds to and prevents the activation of cyclin E-CDK2...
Human ANGPT1 is a secreted ligand for Tie-2, a cell surface receptor tyrosine kinase expressed in endothelial and hemopoietic cells. This protein is...
AK5, is a member of the adenylate kinase family, which is involved in regulating the adenine nucleotide composition within a cell by catalyzing the...
ADSL, is an enzyme that converts adenylosuccinate to AMP and fumarate as part of the purine nucleotide cycle. Defects in ADSL are the cause of...
ACADL belongs to the acyl-CoA dehydrogenase family, existing as a homotetramer. It is involved in the catabolism of fatty acids and aa and they provide a...
Synuclein is a small, soluble protein primarily expressed in neural tissue. The synuclein family includes three known proteins: a-synuclein, b-synuclein, and...
Myoglobin is a cytoplasmic hemoprotein, expressed solely in cardiac myocytes and oxidative skeletal muscle fibers, that reversibly binds O2 by its heme...
Moesin (for membrane-organizing extension spike protein) is a member of the ERM protein family which includes ezrin and radixin. The ERM proteins have a...
The inhibitor of caspase-3-activated DNase (ICAD) is a caspase 3 substrate that controls nuclear apoptosis. ICAD has two isoforms: a functional isoform of...
Heat shock proteins are ubiquitous proteins and have been characterized as cytoprotective molecular chaperones. The typical function of a chaperone is to...
Parkinson's disease (PD) is the second most common neurodegenerative disorder after Alzheimer's disease, with a prevalence of 1-2% in population aged 65...