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Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents....
Component of the 9-1-1 cell-cycle checkpoint response complex that plays a major role in DNA repair. The 9-1-1 complex is recruited to DNA lesion upon damage...
Rho GTPases control a variety of cellular processes. There are 3 subtypes of Rho GTPases in the Ras superfamily of small G proteins: RHO (see MIM 165370),...
DNA binding protein involved in regulation of transcription. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested....
The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It may be involved in small GTPase mediated signal transduction and...
A Rab11 effector protein involved in the endosomal recycling process. Also involved in controlling membrane trafficking along the phagocytic pathway and in...
The protein encoded by this gene belongs to the small GTPase superfamily, Rab family. It is associated with both constitutive and regulated secretory...
Members of the Rab protein family are nontransforming monomeric GTP-binding proteins of the Ras superfamily that contain 4 highly conserved regions involved...
RNA-binding protein that plays a central role in myelinization. Binds to the 5'-NACUAAY-N(1,20)-UAAY-3' RNA core sequence. Acts by regulating pre-mRNA...
Protein serine phosphatase that dephosphorylates 'Ser-3' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates...
Apoptosis is related to many diseases and development. The p53 tumor-suppressor protein induces apoptosis through transcriptional activation of several...
PUM2 is a member of the PUF family, evolutionarily conserved RNA-binding proteins related to the Pumilio proteins of Drosophila and the fem-3 mRNA binding...
PITX3 is a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. Members of this family act as transcription...
PTIP facilitates ATM-mediated activation of p53 and promotes cellular resistance to ionizing radiation. Tandem BRCT (BRCA1 carboxyl-terminal) domains in PTIP...
Transcriptional activator. Required for exocrine pancreatic development. Applications: Suitable for use in ELISA. Other applications not tested. Recommended...
Mutations in the PTEN-induced kinase (PINK1) gene located within the PARK6 locus on chromosome 1p35-p36 have recently been identified in patients with...
May play an important role in regulating differentiation, survival and aggressiveness of the tumor cells. Applications: Suitable for use in ELISA and Western...
Involved in pre-mRNA splicing. Required for U4/U6.U5 tri-snRNP formation. Applications: Suitable for use in ELISA and Western Blot. Other applications not...
Involved in pre-mRNA splicing. Required for U4/U6.U5 tri-snRNP formation. Applications: Suitable for use in ELISA and Western Blot. Other applications not...
Potential calcium-dependent cell-adhesion protein. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended...
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