Receptor for neuropeptide Y and peptide YY. The activity of this receptor is mediated by G proteins that inhibit adenylate cyclase activity. Seems to be...
Neurogenin-1 appears to mediate neuronal differentiation. It requires dimerisation with another basic-helix-loop-helix protein for efficient DNA binding. Its...
Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced...
Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:2000 Western Blot: 1-3ug/ml Optimal...
Transcriptional regulator implicated in neuronal determination. Mediates calcium-dependent transcription activation by binding to E box-containing promoter....
NgR, also named reticulon 4 receptor, is a glycosylphosphoinositol (GPI)-anchored protein that belongs to the family of leucine-rich repeat proteins. NgR...
NENF is a secreted protein that is expressed in neurons but not glial cells of the brain. This protein has neurotrophic activity in primary cultured mouse...
Low affinity receptor which can bind to NGF, BDNF, NT-3, and NT-4. Can mediate cell survival as well as cell death of neural cells. Applications: Suitable...
Neuroligin-1 is a neuronal cell surface protein belonging to the type-B carboxylesterase/lipase family. It is a necessary component in the maturation of...
NTNG1 promotes neurite outgrowth of both axons and dendrites. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution:...
NEK7 encodes a NEK type protein kinase, which contains a C-terminal NIMA-like catalytic domain. NEK7 expression has been documented in normal human blood,...
Protein kinase which plays an important role in mitotic cell cycle progression. Required for microtubule nucleation activity of the centrosome, robust...
Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a...
E3 ubiquitin-protein ligase that mediates ubiquitination of TP73. Acts to stabilize TP73 and enhance activation of transcription by TP73. Applications:...
Required for mitosis progression. Promotes the nucleation of microtubules from the spindle. Applications: Suitable for use in ELISA and Western Blot. Other...
Acts as a component of the essential kinetochore-associated NDC80 complex, which is required for chromosome segregation and spindle checkpoint activity....
Cation exchanger involved in pigmentation, possibly by participating in ion transport in melanosomes. Probably transports 1 Ca2+ and 1 K+ in exchange for 4...
Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling....
May play important roles in selective fasciculation and zone-to-zone projection of the primary olfactory axons. Applications: Suitable for use in ELISA....
Mediates the voltage-dependent sodium ion permeability of excitable membranes. Assuming opened or closed conformations in response to the voltage difference...