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Acid sphingomyelinase (ASM) is a lysosomal protein that hydrolyzes sphingomyelin to ceramide and phosphocholine. The ASM gene encodes three proteins, ASM-1,...
The intestinal alkaline phosphatase gene (ALPI) encodes a digestive brush-border enzyme, IAP (also designated ALP), which is highly upregulated during small...
Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2, a cell surface receptor tyrosine kinase expressed in endothelial and hemopoietic cells. Ang-1 is an...
The sodium channel protein type 8 subunit alpha (Na+ CP type VIIIalpha ) is a multi-pass, transmembrane protein that mediates the sodium ion permeability of...
Profilins (Profilin-1, Profilin-2 and Profilin-3) act as nucleotide exchange factors that use ATP to charge Actin, a process that regulates Actin...
Interleukin-7 (IL-7) was originally described as a factor capable of inducing in vitro proliferation of pre-B cells from marrow cultures. The IL-7 gene...
CD9 is a type IV transmembrane glycoprotein with four transmembrane domains. CD9 on pre-B cells may play a role in cell-cell adhesion. In addition, CD9 may...
The T cell receptor (TCR) is a heterodimer composed of either alpha and beta or gamma and delta chains. CD3 chains and the CD4 or CD8 co-receptors are also...
NK4R is a putative Tachykinin Receptor with sequence similarities to the neuromedin K receptor. It was initially thought to be an opioid receptor and is...
G protein-coupled receptor 81 (FKSG80) belongs to the G protein-coupled receptor 1 family. It is an integral membrane protein which functions as an orphan...
Probable G-protein coupled receptor 179 is a protein that in humans is encoded by the GPR179 gene. This gene encodes a member of the glutamate receptor...
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins...
In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates...
CNS white matter is selectively inhibitory for axonal outgrowth. Nogo is an oligodendrocyte-specific member of the reticulon family and is a component of CNS...
Tryptase gamma, also known as serine protease 31 or transmembrane tryptase, is an enzyme that in humans is encoded by the TPSG1 gene. Tryptases comprise a...
Matrix-remodeling-associated protein 5 (MXRA5), also known as adhesion protein with leucine-rich repeats and immunoglobulin domains related to perlecan...
Thioredoxin 2 (Trx-2) is a small redox protein that is localized to the mitochondria and is essential for cell viability, playing a crucial role in the...
CLEC-14A (C-type lectin domain family 14 member A), also known as EGFR-5 (epidermal growth factor receptor 5) or CEG1, is a 490 amino acid single-pass type I...
ADAM (a disintegrin and metalloprotease) proteins are a family of over 30 membrane-anchored, glycosylated, Zn2+ dependent proteases that are involved in...
Midkine, or MK, is a heparin-binding molecule involved in the regulation of growth and differentiation during embryogenesis. MK expression is tightly...
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