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The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of...
The CCAAT-binding factor NF-Y is a heteromeric transcription factor that specifically binds to CCAAT sequences in many eukaryotic genes. NF-Y is made up of...
Differentiation of myogenic cells is regulated by multiple positively and negatively acting factors. One well characterized family of helix-loop-helix (HLH)...
Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of poly-peptides that contribute to mRNA transcription and pre-mRNA processing as well as...
Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. This gene encodes a ubiquitous form of...
T cell factors (TCFs) comprise a family of DNA-binding transcriptional activators that are essential for lymphoid cell development. These transcription...
The second messenger cyclic AMP (cAMP) mediates diverse cellular responses to external signals such as proliferation, ion transport, regulation of metabolism...
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or...
TROP-2, also known as tumor-associated calcium signal transducer 2 (TACSTD2), pancreatic carcinoma marker protein GA733-1, membrane component chromosome 1,...
Hexosaminidase B (HEXB), also designated beta-hexosaminidase B, is a Hexosaminidase B (HEXB), also designated b-hexosaminidase B, is a tetramer of two b-A...
Histone H10 (H1 histone family, member 0) is a lysine rich member of the H1 family of linker histones. The H1 family of proteins interacts with linker DNA...
In each of these species, the c-Mos proto-oncogene locus consists of a single exon which encodes Mos, a serine/threonine protein kinase involved in the...
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or...
Hexamethylene bis-acetamide inducible 1 (HEXIM1) and Hexamethylene bis-acetamide inducible 2 (HEXIM2) comprise a family of proteins which inhibit positive...
Activation of FUSE, the far-upstream element, is required for the proper expression of the mammalian gene c-myc. The binding of FBP (FUSE-binding protein) to...
ST18 (suppression of tumorigenicity 18), also known as ZNF387 ((zinc finger protein 387), is a 1,047 amino acid nuclear protein that is expressed at low...
Mixed lineage kinases (MLKs) are a family of protein kinases sharing two leucine zipper-like motifs which mediate protein dimerization, and a kinase domain...
The Ovo family of zinc-finger transcription factors encode evolutionarily conserved genes including those from Caenorhabditis elegans, Drosophila...
PIG11 (p53-induced gene 11 protein), also known as TP53I11, is a 177 amino acid tumor suppressor belonging to the p53-induced protein gene (PIG) family. The...
A total of eight mammalian PLC isozymes have been described (PLC (beta)1, PLC (beta)2, PLC (beta)3, PLC (beta)4, PLC (gamma)1, PLC (gamma)2, PLC (delta)1 and...
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