Integrins are heterodimers composed of noncovalently associated transmembrane (alpha) and (beta) subunits. The 16 (alpha) and 8 (beta) subunits...
The cathepsin family of proteolytic enzymes contains several diverse classes of proteases. The cysteine protease class comprises cathepsins B, L, H, K, S,...
Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as...
Matrix metalloproteinases (MMPs) are highly homologous Zn2+ endopeptidases involved in extracellular matrix breakdown. MMP mediated extracellular remodeling...
Integrins are heterodimers composed of noncovalently associated transmembrane (alpha) and (beta) subunits. The 16 (alpha) and 8 (beta) subunits...
Integrins are heterodimers composed of noncovalently associated transmembrane (alpha) and (beta) subunits. The 16 (alpha) and 8 (beta) subunits...
The complement component proteins, C1, C3, C4, and C5, are potent anaphylatoxins that are released during complement activation. Binding of these proteins to...
Caspase-5 (also designated ICErel-III, TY, ICH-3 and caspase-12 in mouse), can cleave its own precursor, an activity that requires the cysteine 245 residue....
PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair in response to environmental stress. This protein can be cleaved...
PARP, a 116 kDa nuclear poly (ADP-ribose) polymerase, appears to be involved in DNA repair in response to environmental stress. This protein can be cleaved...
The LIN-12/Notch family of transmembrane receptors is believed to play a central role in development by regulating cell fate decisions. To date, four Notch...
Kallikreins (KLKs) belong to the serine protease family of proteolytic enzymes. Kallikrein-8 (KLK8), also called neuropsin precursor, ovasin or serine...
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen,...
The matrix metalloproteinases (MMP) are a family of peptidase enzymes responsible for the degradation of extracellular matrix components, including collagen,...
The cathepsin family of proteolytic enzymes include several diverse classes of proteases. Cathepsins B, L, H, K, S and O comprise the cysteine protease...
The inter-(alpha) trypsin inhibitor (ITI) family is a group of structurally related plasma serine protease inhibitors synthesized in the liver and built up...
Integrins are heterodimers composed of noncovalently associated transmembrane a and b subunits. The 16 a and 8 b subunits heterodimerize to produce more than...
The Eph subfamily represents the largest group of receptor protein kinases identified to date. There is increasing evidence that Eph family members are...
MBL is a key component in immune response in that it can directly trigger neutralization of invading microorganisms by an Ab-independent mechanism. Mutations...
The extensive family of COL gene products (collagens) is composed of several chain types, including fibril-forming interstitial Collagens (Types I, II, III...