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Deubiquitinating enzyme involved in protein homeostasis maintenance, transcription, cytoskeleton regulation, myogenesis and degradation of misfolded...
Trypsin is a 24 kDa enzyme of the serine proteinase family. It is produced in the pancreas as an inactive precursor, trypsinogen, but the active enzyme is...
Seems to play a role in epithelial tight junction formation. Appears early in primordial forms of cell junctions and recruits PARD3. The association of the...
Transcriptional regulator. May participate in transcriptional regulation through the recruitment of SETDB1 histone methyltransferase and subsequent...
Gonadotropin (also designated choriogonadotropin) is a hormone produced by the placenta in the first trimester of pregnancy and exists as a heterodimer...
The CD3 complex mediates signal transduction. Defects in CD3D are a cause of severe combined immunodeficiency autosomal recessive...
A proliferation-inducing ligand (APRIL), also designated TNFSF13, is a Type II membrane protein that shares characteristics with other members of the tumor...
Receptor for the cytotoxic ligand TNFSF10/TRAIL. The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing...
Syndecan-1 (SYND1), also designated CD138, is a type I integral membrane proteoglycan that contains both chondroitin sulfate and heparan sulfate groups. It...
Thought to participate in the regulation of the phospholipid metabolism in biomembranes including eicosanoid biosynthesis. Catalyzes the calcium-dependent...
Natural killer (NK) cells are lymphocytes that can mediate lysis of certain tumor cells and virus-infected cells without previous activation. They can also...
This protein is a minor sialoglycoprotein in human erythrocyte membranes. The blood group Gerbich antigens and receptors for Plasmodium falciparum merozoites...
Transition from G1 to S phase requires the association of Cdc28 with members of the G1 cyclin family. Exit from mitosis and initiation of the next cell cycle...
The biological effects of IL7 are mediated by the binding of IL7 to the specific cell surface receptor. The functional high-affinity IL7 receptor consists of...
AMPK is a heterotrimeric complex comprising a catalytic (alpha) subunit and regulatory (beta) and (gamma) subunits. It protects cells from stresses that...
Avoidance by host tissues of attack by autologous complement proteins is dependent in part on the activities of membrane regulatory factors. One molecule...
Catalyzes the NADPH-dependent reduction of succinic semialdehyde to gamma-hydroxybutyrate. May have an important role in producing the neuromodulator...
ALDH1A1, also designated retinal dehydrogenase 1 (RalDH1 or RALDH1); aldehyde dehydrogenase family 1 member A1; aldehyde dehydrogenase cytosolic; ALDHII;...
Probably interacts with SEMA5A. Expressed at highest levels in ascending colon and at moderate levels in adult kidney. Expressed at low levels in adult...
The cystatin superfamily is a well-established family of cysteine protease inhibitors. All true cystatins inhibit cysteine peptidases of the papain family,...
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