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Heme oxygenases are microsomal enzymes that cleave heme to produce the antioxidant biliverdin, inorganic iron and carbon monoxide (CO). The activity of Heme...
MerTK, also called c-Mer, is a member of the Mer/Axl/Tyro3 receptor kinase family. It is a 984 residue transmembrane protein made up of one tyrosine kinase...
ECA39, also known as BCAT1 (branched-chain-amino-acid aminotransferase 1, cytosolic) is localized to the cytoplasm where it forms a homodimer. ECA39 is...
Acid sphingomyelinase (ASM) is a lysosomal protein that hydrolyzes sphingomyelin to ceramide and phosphocholine. The ASM gene encodes three proteins, ASM-1,...
The intestinal alkaline phosphatase gene (ALPI) encodes a digestive brush-border enzyme, IAP (also designated ALP), which is highly upregulated during small...
Neuregulin-1 gene, NRG1, encodes numerous splice variants with differing transcription initiation sites. Neuregulin-1 includes a range of isoforms with...
Angiopoietin-1 (Ang-1) is a secreted ligand for Tie-2, a cell surface receptor tyrosine kinase expressed in endothelial and hemopoietic cells. Ang-1 is an...
The sodium channel protein type 8 subunit alpha (Na+ CP type VIII(alpha) ) is a multi-pass, transmembrane protein that mediates the sodium ion permeability...
Profilins (Profilin-1, Profilin-2 and Profilin-3) act as nucleotide exchange factors that use ATP to charge Actin, a process that regulates Actin...
Interleukin-7 (IL-7) was originally described as a factor capable of inducing in vitro proliferation of pre-B cells from marrow cultures. The IL-7 gene...
The human endothelins represent a gene family comprised of endothelin-1, endothelin-2, and endothelin-3, also known as ET-1, ET-2, and ET-3. Endothelins can...
CD9 is a type IV transmembrane glycoprotein with four transmembrane domains. CD9 on pre-B cells may play a role in cell-cell adhesion. In addition, CD9 may...
The T cell receptor (TCR) is a heterodimer composed of either (alpha) and (beta) or (gamma) and (delta) chains. CD3 chains and the CD4 or CD8 co-receptors...
NK4R is a putative Tachykinin Receptor with sequence similarities to the neuromedin K receptor. It was initially thought to be an opioid receptor and is...
G protein-coupled receptor 81 (FKSG80) belongs to the G protein-coupled receptor 1 family. It is an integral membrane protein which functions as an orphan...
Probable G-protein coupled receptor 179 is a protein that in humans is encoded by the GPR179 gene. This gene encodes a member of the glutamate receptor...
G protein-coupled receptors (GPRs), also known as seven transmembrane receptors, heptahelical receptors or 7TM receptors, comprise a superfamily of proteins...
Fibroblast growth factor-1 (FGF-1), also designated acidic FGF, and fibroblast growth factor-2 (FGF-2), also designated basic FGF, are members of a family of...
In platelets and gut, serotonin plays a major role in cardiovascular function and motility of the gastrointestinal tract, respectively. Serotonin mediates...
CNS white matter is selectively inhibitory for axonal outgrowth. Nogo is an oligodendrocyte-specific member of the reticulon family and is a component of CNS...
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