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The cell cycle is controlled in part by cyclin dependent kinases (CDKs) which are themselves controlled by modifications such as phosphorylation of CDKs and...
Adrenergic Receptors (ARs) are members of the 7-transmembrane domain G-protein-coupled receptor superfamily that bind the endogenous catecholamines...
The glutamate receptor 2, a homo- or heter0teramer, is an Ionotropic glutamate receptor. L-glutamate acts as an e, Xenopus/Amphibian,citatory...
Collagen 1, alpha 1 propeptide (COL1A1) is a member of group I collagen (fibrillar forming collagen). Defects in COL1A1 are the cause of Caffey disease...
Heat shock factor protein 1 (HSF1) is a DNA-binding protein that specifically binds heat shock promoter elements (HSE) and activates transcription. HSF1 is...
Cytokeratin-8 (Type II cytoskeletal keratin 8), together with KRT19, helps to link the contractile apparatus to dystrophin at the costameres of striated...
Collagen 1, alpha 1 propeptide (COL1A1) is a member of group I collagen (fibrillar forming collagen). Defects in COL1A1 are the cause of Caffey disease...
RAC-alpha serine/threonine-protein kinase (AKT1) signals downstream of phosphatidylinositol 3-kinase (PI3K) to mediate the effects of various growth factors...
Nijmegen breakage syndrome protein 1 (NBS1) is a component of the MRE11/RAD50/NBN (MRN) comple, Xenopus/Amphibian,, which plays a critical role in the...
Parafibromin (CDC73) is a tumor suppressor involved in transcriptional and post-transcriptional control pathways, such as cell cycle progression through the...
Upon ligand binding, BMPR1A forms a receptor comple, Xenopus/Amphibian, consisting of two type II and two type I transmembrane Ser/Thr kinases. The type I...
Retinoblastoma-associated protein (Rb) is a key regulator of entry into cell division that acts as a tumor suppressor. Rb is directly involved in the...
PTCH1 is a receptor for sonic hedgehog, indian hedgehog and desert hedgehog that associates with the smoothened protein to transduce the hedgehog's protein...
The adenomatous polyposis coli protein (APC) is a tumor suppressor that promotes rapid degradation of catenin-beta 1 (CTNNB1) and participates in Wnt...
Actins are highly conserved proteins involved in cell motility that are ubiquitously e, Xenopus/Amphibian,pressed in eukaryotic cells. There are 3 main actin...
Matri, Xenopus/Amphibian, metalloproteinase protein family (MMP) is involved in the breakdown of e, Xenopus/Amphibian,tracellular matri, Xenopus/Amphibian,...
Matri, Xenopus/Amphibian, metalloproteinase protein family (MMP) is involved in the breakdown of e, Xenopus/Amphibian,tracellular matri, Xenopus/Amphibian,...
Leptin, the product of the ob (obese) gene, is a 16 kDa-protein consisting of 146 amino acid residues. Leptin is produced in the adipose tissue, and has an...
Glucose transporter type 4 (GLUT4 or SLC2A4) is the facilitated glucose transporter e, Xenopus/Amphibian,clusively e, Xenopus/Amphibian,pressed in adipocytes...
Tissue inhibitor of metalloproteinases 3 comple, Xenopus/Amphibian,es with metalloproteinases (such as collagenases) and irreversibly inactivates them by...
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