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Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key...
Caspases mediate essential key proteolytic events in inflammatory cascades and the apoptotic cell death pathway. Caspase 12 is involved in the apoptosis...
Caspases mediate essential key proteolytic events in inflammatory cascades and the apoptotic cell death pathway. Caspase 12 is involved in the apoptosis...
Three distinct signaling pathways lead to programmed cell death (apoptosis). The death receptor and mitochondrion pathways are the mains, in which the key...
Caspases are a family of cysteine proteases that are key mediators of programmed cell death or apoptosis. The precursor form of all caspases is composed of a...
Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. Caspase-12 (CASP12) process inflammatory...
Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. Caspase-12 (CASP12) process inflammatory...
Caspase-12 is located in the endoplasmic reticulum (ER). A non-caspase protease, calpain, upon activation by elevated intracellular calcium, may be...
Murine caspase-11 is an upstream protease of caspase-1 and interacts with the proform of caspase-1 which in turn activates IL-1 beta. Caspase-11 is not...
Caspase-11, (also known as CASP-11, ICH-3, ICE-B) promotes IL-b processing by procaspase-1 (ICE) and therefore may also have a role in inflammatory response...
There are two types of apoptotic caspases, initiator (apical) caspases and effector (executioner) caspases. Caspase 10 is one of the initiator caspases that...
Applications: Suitable for use in Immunohistochemistry. Other applications not tested. Recommended Dilution: Immunohistochemistry (paraffin): 1:50-1:100...
A unique family of cysteine proteases has been described that differs in sequence, structure and substrate specificity from any previously described protease...
Caspases are death effector domain-containing cysteine aspartases presumed to be at or near the apex of apoptotic signaling pathways. All known isoforms of...
Apoptosis, or programmed cell death, is a common property of all multicellular organisms. The current dogma of apoptosis suggests that the components of the...
Apoptosis, or programmed cell death, is a common property of all multicellular organisms. The current dogma of apoptosis suggests that the components of the...
Apoptosis, or programmed cell death, is a common property of all multicellular organisms. The current dogma of apoptosis suggests that the components of the...
Caspases are death effector domain-containing cysteine aspartases presumed to be at or near the apex of apoptotic signaling pathways. All known isoforms of...
Caspase 10 belongs to the peptidase C14A family. It is involved in the caspase activation cascade and is responsible for the execution of apoptosis. Caspase...
Caspase 10 belongs to the peptidase C14A family. It is involved in the caspase activation cascade and the execution of apoptosis. Caspase 10 is recruited to...
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