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This gene encodes the enzyme that metabolizes thiopurine drugs via S-adenosyl-L-methionine as the S-methyl donor and S-adenosyl-L-homocysteine as a...
Essential component of the NELF complex, a complex that negatively regulates the elongation of transcription by RNA polymerase II. The NELF complex, which...
Plays a central role in late thymocyte development by controlling both positive and negative T-cell selection. Required to sustain and/or integrate signals...
Transcriptional repressor, which probably repress transcription by binding directly the 5'-CTGTCAA-3' DNA sequence or by interacting with TGF-beta activated...
Involved in primary cilium biogenesis. Applications: Suitable for use in Immunofluorescence, ELISA and Immunohistochemistry. Other applications not tested....
The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the...
Catalyzes the conversion of methylcytosine (5mC) to 5-hydroxymethylcytosine (hmC). Plays an important role in the regulation of myelopoiesis. The clear...
Tensin 1 may be involved in cell migration, cartilage development and in linking signal transduction pathways to the cytoskeleton. Applications: Suitable for...
TERF1 is a telomere specific protein which is a component of the telomere nucleoprotein complex. This protein is present at telomeres throughout the cell...
Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting...
Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex...
TCP1 is member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked...
Putative transcription factor. Isoform 3 may play a role in early spermatogenesis. Applications: Suitable for use in ELISA and Western Blot. Other...
SC1 is a extracellular matrix glycoprotein playing an important role in neural developmental processes like axon guidance and synaptogenesis. Higher...
Transcription factor, probably binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Applications: Suitable for use in ELISA and Western Blot. Other...
Transcriptional activator that regulates the tissue specific expression of multiple genes, especially in pancreatic islet cells and in liver. Required for...
Enhances the phosphorylation and activation of AKT1, AKT2 and AKT3. Promotes nuclear translocation of AKT1. Enhances cell proliferation, stabilizes...
TBC1D4 may act as a GTPase-activating protein for RAB2A, RAB8A, RAB10 and RAB14. Isoform 2 promotes insulin-induced glucose transporter SLC2A4/GLUT4...
TAS1R2 is a Taste Receptor. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilution: ELISA: 1:32,000...
Probable role in protein transport. May regulate growth factor-induced mitogenic signaling. Applications: Suitable for use in ELISA and Western Blot. Other...
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