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Essential PPIase that regulates mitosis presumably by interacting with NIMA and attenuating its mitosis-promoting activity. Displays a preference for an...
Probable adapter protein that bind to and organize the subcellular localization of a variety of membrane proteins containing some PDZ recognition sequence....
Acts as a transcriptional regulator of muscle creatine kinase (MCK) and so has a role in the establishment of diverse mesodermal muscle types. The protein...
Protein phosphorylation is an important posttranslational modification that serves many key functions to regulate a protein's activity, localization, and...
Catalyzes the last step in the biosynthesis of serine from carbohydrates. The reaction mechanism proceeds via the formation of a phosphoryl-enzyme...
Exhibits PLA1/2 activity, catalyzing the calcium-independent hydrolysis of acyl groups in various phosphotidylcholines (PC) and phosphatidylethanolamine...
PLA2G4A is a member of the cytosolic phospholipase A2 group IV family. The enzyme catalyzes the hydrolysis of membrane phospholipids to release arachidonic...
Cyclic nucleotide phosphodiesterase with a dual-specificity for the second messengers cAMP and cGMP, which are key regulators of many important physiological...
PDE11A is a 100kD cyclic nucleotide phosphodiesterase, which catalyzes the hydrolysis of cAMP and cGMP. PDE11A is thought to be involved in multiple...
Hydrolyzes the second messenger cAMP, which is a key regulator of many important physiological processes. Applications: Suitable for use in ELISA and Western...
PHLPP2, a protein phosphatase and negative regulator, which mediates the inactivation of Akt and protein kinase C (PKC) activity, through the direct...
p53/TP53-regulated repressor of Akt/AKT1 signaling. Represses AKT1 by preventing AKT1-binding to membrane lipids, thereby inhibiting AKT1 translocation to...
This gene, which is a member of the tetraspanin superfamily, is one of several tumor-suppressing subtransferable fragments located in the imprinted gene...
Cellular oxygen sensor that catalyzes, under normoxic conditions, the post-translational formation of 4-hydroxyproline in hypoxia-inducible factor (HIF)...
Multifunctional protein working as a cell cycle progression factor as well as a cell survival factor. Required for the progression from the G1 to the S...
Transcriptional coactivator for steroid receptors and nuclear receptors. Greatly increases the transcriptional activity of PPARG and thyroid hormone receptor...
The p53 tumor-suppressor gene integrates numerous signals that control cell life and death. PERP, also termed PIGPC1 and THW, is a plasma membrane protein....
Probably required for protein import into peroxisomes. Anchors PEX1 and PEX6 to peroxisome membranes, possibly to form heteromeric AAA ATPase complexes...
Required for protein import into peroxisomes. Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:8000...
Somewhat implicated in the biogenesis of peroxisomes. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended...
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