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TAFA proteins are a newly discovered family of proteins, which are distantly related to MIP-1a, a member of the CC-chemokine family. TAFA mRNAs are highly...
TSLP is a hemopoietic protein that is expressed in the heart, liver and prostate. TSLP overlaps biological activities with IL-7 and binds with the...
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are secreted in the gastrointestinal tract, and appear to play an important role in intestinal mucosal...
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal...
The Trefoil Factor peptides (TFF1, TFF2 and TFF3) are expressed in the gastrointestinal tract, and appear to play an important role in intestinal mucosal...
Encoded by the ob (obese) gene, Leptin is an adipose-derived cytokine that suppresses appetite and increases thermogenesis. Leptin exerts its anorectic...
TPO is a lineage specific growth factor, produced in the liver, kidney and skeletal muscle. It stimulates the proliferation and maturation of megakaryocytes,...
Oncostatin M (OSM) is a growth and differentiation factor that participates in the regulation of neurogenesis, osteogenesis and hematopoiesis. Produced by...
IFN lambda-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three...
IFN -u-1,-2, and -3 (also known as IL-29, IL-28A and IL-28B respectively) are distantly related to the IL-10 family and Interferons. All three IFN-lambdas...
Proteins of this family play an important role in inducing non-specific resistance against a broad range of viral infections. They also affect cell...
IFN-g is an acid-labile interferon produced by CD4 and CD8 T lymphocytes as well as activated NK cells. IFN-g receptors are present in most immune cells,...
TNF-beta is a potent mediator of inflammatory and immune responses. It belongs to the TNF superfamily of ligands and signals through TNFR1 and TNFR2....
Human IL-33 is a proinflammatory protein that shares structural and functional characteristics with the IL-1 cytokine family. It binds and signals through...
Human IL-31 is a T-cell derived cytokine that shares several structural and functional characteristics with IL-6, Oncostatin M, LIF, and Cardiotrophin-1. It...
IL-17B is a disulfide-linked homodimer of two 161aa polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly...
IL-17D is a disulfide-linked homodimer of two 185aa polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly...
IL-17F, a member of the IL-17 family of structurally related cytokines, has been shown to stimulate proliferation and activation of T-cells and PBMCs. IL-17F...
IL-17E is a disulfide-linked homodimer of two 145aa polypeptide chains. It belongs to the IL-17 family of structurally-related cytokines that share a highly...
IL-22 is a member of the IL-10 family of regulatory cytokines which includes IL-10, IL-19, IL-20, IL-22, IL-24 and IL-26. Members of this family share...
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