LRP3 is a probable receptor, widely expressed, which may be involved in the internalization of lipophilic molecules and/or signal transduction. Its precise...
Tyrosinase (TYR), a type I membrane protein and copper-containing enzyme,is involved in the production of melanin, the primary pigment found in...
CEP290 activates ATF4 mediated transcription and is required for the correct localization of ciliary and phototransduction proteins in retinal photoreceptor...
Six5 (homeobox protein SIX5), also known as SIX5, BOR2 or DMAHP (DM locus-associated homeodomain protein), is a transcription factor that is expressed in...
Members of the NK-2 family of homeodomain proteins are key regulators of growth and development in several tissues, including brain, heart and...
HOX genes are a class of homeodomain-containing transcription factors. They play key roles in embryonic development and hematopoeisis. HOXA6 is part of a...
GNL1 (guanine nucleotide-binding protein-like 1) is a nuclear protein that likely acts as a regulator of the histocompatibility cluster. GNL1 and MMR1, the...
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors...
Heterotrimeric G proteins function to relay information from cell surface receptors to intracellular effectors. Each of a very broad range of receptors...
The Golgi apparatus is a highly complex organelle comprised of a stack of cisternal membranes on the secretory pathway from the ER to the cell surface. The...
Glial cell line-derived neurotrophic factor (GDNF) and the related neurotrophic factor neurturin (NTN) are potent survival factors for central and peripheral...
The (gamma)-Tubulin complex is composed of (gamma) Tubulin and the (gamma)-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which...
The (gamma)-Tubulin complex is composed of (gamma) Tubulin and the (gamma)-Tubulin complexassociated proteins GCP2, GCP3, GCP4, GCP5 and GCP6, all of which...
The forkhead-box (FOX) genes comprise a superfamily of at least 43 members that express proteins which are involved in transcriptional regulation and may be...
The Forkhead-box (FOX) genes comprise a superfamily of at least 43 members that encode proteins which are involved in transcriptional regulation and may be...
Activation of FUSE, the far-upstream element, is required for the proper expression of the mammalian gene c-Myc in undifferentiated cells. The binding of FBP...
Translation initiation in eukaryotes necessitates the assembly of an 80S ribosomal complex containing methionyl initiator tRNA (Met-tRNAiMet), which is base...
POLR3A (polymerase (RNA) III (DNA directed) polypeptide A), also known as RPC1 or RPC155, is a 1,390 amino acid protein that localizes to the nucleus and...
C1q, a subcomponent of the classical complement pathway, mediates its activation and thereby plays an important role in immune response. The presence of...
Membrane and vesicular trafficking in the early secretory pathway are mediated by non-Clathrin COP (coat protein) I-coated vesicles. COPI-coated vesicles...