Required for autophagy. SUBUNIT: Conjugated to ATG5. Cellular Localization: Cytoplasm. Alternative Products: 2 named isoforms produced by alternative...
Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage...
Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:12,8000 (0.0781ug/ml) Optimal dilutions to be...
Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage...
Applications: Suitable for use in ELISA. Other applications not tested. Recommended Dilution: ELISA: 1:12,800 (0.078ug/ml) Optimal dilutions to be determined...
GABARAPL1 (GABARAPL2 or GABARAP or MAP1LC3)-modifier protein conjugating enzyme involved in its E2-like covalent binding to PE. ATG7 (E1-like enzyme)...
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A...
Cysteine protease required for autophagy, which cleaves the C-terminal part of either MAP1LC3, GABARAPL2 or GABARAP, allowing the liberation of form I. A...
Apg7 is the human gene product similar in homology to Pichia pastoris GSA7 and Saccharomyces cerevisiae Apg7. In the yeast, the protein appears to be...
In mammalian cells, Autophagy-related protein 7 is essential for autophagy conjugation systems, autophagosome formation, starvation-induced bulk degradation...
Functions as an E1 enzyme essential for multisubstrates such as GABARAPL1 and ATG12. Forms intermediate conjugates with GABARAPL1 (GABARAPL2, GABARAP or...
APEX2 may participate in both nuclear and mitochondrial post-replicative base excision repair (BER). In the nucleus functions in the PCNA-dependent BER...
APE1 repairs oxidative DNA damages in vitro. It may also play a role in preventing cell death by suppressing mutations. APE1 removes the blocking groups from...
Human A (MW: 38kD) endonuclease-1 (HAP-1), also known as APE, APEX or Ref-1, is a nuclear enzyme that repairs apurinic/apyramidinic sites in cellular DNA....
Human apurinic (apyrimidinic) endonuclease:redox-factor 1 (APE/Ref-1) is involved in the repair of DNA damage as well as in the transcriptional regulation of...
Human apurinic (apyrimidinic) endonuclease:redox-factor 1 (APE/Ref-1) is involved in the repair of DNA damage as well as in the transcriptional regulation of...
Reactive oxygen species (H2O2
Anaphase-promoting complex (APC) is homologous to the two highly conserved RING finger proteins ROC1 and ROC2. APC11 specifically interacts with APC2, a...
APC is a ubiquitin ligase which specifically targets mitotic regulatory factors such as Pds 1/Cut 2 and cyclin B. It was found that APC 10/Doc 1 is localized...
The anaphase-promoting complex (APC) consists of at least 8 protein subunits, including APC5, CDC27 (APC3; MIM 116946), CDC16 (APC6; MIM 603461), and CDC23...